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KMID : 0380519980020020107
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Korean Journal of Veterinary Pathology
1998 Volume.2 No. 2 p.107 ~ p.116
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Pathological findings of experimentally infected piglets with a porcine epidemic diarrhea virus isolated in Korea
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Kim Gye-Yeop
Park Nam-Yong
Chung Chi-Young
Park Young-Seok
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Abstract
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Twelve colostrum-deprived piglets were inoculated oral1y with porcine epidemic diarrhea virus isolated from Korea. The piglets were euthanatized from at 12 hour postinoculation(PI) at 6-hour intervals. At 24 to 36 hours PI, all infected piglets showed severe yellowish to watery diarrhea, dehydration, depression, and anorexia. At necropsy, the intestinal wall looked thin, mesenteric vessels congested, and mesenteric lymph nodes edematous. The histological findings showed marked villous atrophy and fusion, severe degeneration of enterocytes and monomuclear cell infiltration in the lamina propria. On electron microscopy, villous epithelial cells of infected jejunum contained viral particles at 18 hour PI. The viral particles were pleomorphic spheres with a mean diameter of 95∼180nm including 18nm projections.
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KEYWORD
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porcine epidemic diarrhea, Korea, PED, swine
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